Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
BMC Public Health. 2018 Jul 11;18(1):864. doi: 10.1186/s12889-018-5762-5.
Vaccination is a cost-effective and life-saving intervention. Recently several new, but more expensive vaccines have become part of immunization programmes in low and middle income countries (LMIC). Monitoring vaccine wastage helps to improve vaccine forecasting and minimise wastage. As the costs of vaccination increases better vaccine management is essential. Many LMIC however do not consistently monitor vaccine wastage.
We conducted two surveys in health facilities in rural and urban Gambia; 1) a prospective six months survey in two regions to estimate vaccine wastage rates and type of wastage for each of the vaccines administered by the Expanded programme on Immunization (EPI) and 2) a nationwide cross sectional survey of health workers from randomly selected facilities to assess knowledge, attitude and practice on vaccine waste management. We used WHO recommended forms and standard questionnaires. Wastage rates were compared to EPI targets.
Wastage rates for the lyophilised vaccines BCG, Measles and Yellow Fever ranged from 18.5-79.0%, 0-30.9% and 0-55.0% respectively, mainly through unused doses at the end of an immunization session. Wastage from the liquid vaccines multi-dose/ single dose vials were minimal, with peaks due to expiry or breakage of the vaccine diluent. We interviewed 80 health workers and observed good knowledge. Batching children for BCG was uncommon (19%) whereas most health workers (73.4%) will open a vial as needed.
National projected wastage targets were met for the multi-dose/single dose vials, but for lyophilised vaccines, the target was only met in the largest major health facility.
接种疫苗是一种具有成本效益和挽救生命的干预措施。最近,一些新的、但更昂贵的疫苗已成为中低收入国家(LMIC)免疫规划的一部分。监测疫苗浪费有助于改善疫苗预测并尽量减少浪费。随着疫苗接种成本的增加,更好的疫苗管理至关重要。然而,许多中低收入国家并未持续监测疫苗浪费情况。
我们在冈比亚农村和城市的卫生机构中进行了两项调查;1)在两个地区进行了为期六个月的前瞻性调查,以估计每种扩大免疫规划(EPI)接种疫苗的浪费率和类型;2)对随机选择的卫生机构的卫生工作者进行全国性横断面调查,以评估疫苗浪费管理方面的知识、态度和实践。我们使用了世界卫生组织推荐的表格和标准问卷。将浪费率与 EPI 目标进行了比较。
冻干疫苗卡介苗、麻疹和黄热病的浪费率分别为 18.5-79.0%、0-30.9%和 0-55.0%,主要是由于免疫接种结束时未使用的剂量造成的。多剂量/单剂量小瓶中的液体疫苗浪费很少,由于疫苗稀释剂过期或破裂而出现峰值。我们采访了 80 名卫生工作者,发现他们的知识水平良好。批量接种卡介苗的情况并不常见(19%),而大多数卫生工作者(73.4%)会按需打开小瓶。
多剂量/单剂量小瓶的国家预计浪费目标已经达到,但对于冻干疫苗,只有最大的主要卫生机构达到了目标。