The INCLEN Trust International, F1/5, Okhla Industrial Area, Phase 1, New Delhi, 110020, India.
Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
BMC Public Health. 2020 Apr 25;20(1):556. doi: 10.1186/s12889-020-08637-1.
Government of India is introducing new and relatively costly vaccines under immunization program. Monitoring of vaccine wastage is needed to guide the program implementation and forecasting. Under pilot introduction of rotavirus vaccine in two districts both 5- and 10-doses vials were used, which was considered as an opportunity for documenting the wastage. The wastage rates for other routine vaccines were also documented.
A survey conducted in two districts (Kangra, Himachal Pradesh and Pune, Maharashtra) covered 49 vaccine stores, 34 sub-centres and 34 outreach sessions collected vaccine receipt, distribution and usage data for two complete years 2016 and 2017.
The overall wastage rates for almost all vaccines were higher in Kangra district (BCG 37.1%, DPT 32.1%, Measles 32.2%, OPV 50.8%, TT 34.1% and pentavalent 18.4%) than Pune district (BCG 35.1%, DPT 25.4%, Measles 21.7%, OPV 14.3%, TT 23.1% and pentavalent 13.2%). Wastage for pneumococcal conjugate and measles-rubella vaccines in Kangra district were 27 and 40.5%, respectively. With transition from 5- to 10-doses vials for rotavirus vaccine, wastage at stores levels increased in both Kangra (29 to 33.2%) and Pune (17.8 to 25.7%) districts. With transition from intramuscular to intradermal fractional inactivated polio vaccine, the wastage increased from 36.1 to 54.8% in Kangra and 18.4 to 26.9% in Pune district.
The observed vaccine wastage rates for several vaccines were relatively higher than program assumption for forecasting. The observed variations in the vaccine wastage indicates need for state or region based documentation and monitoring in India for appropriate programmatic action.
印度政府正在免疫计划下引入新的且相对昂贵的疫苗。为了指导计划的实施和预测,需要监测疫苗浪费情况。在两个地区(喜马偕尔邦的 Kangra 和马哈拉施特拉邦的浦那)进行轮状病毒疫苗试点引入时,使用了 5 剂和 10 剂小瓶,这被认为是记录浪费情况的机会。还记录了其他常规疫苗的浪费率。
在两个地区(喜马偕尔邦的 Kangra 和马哈拉施特拉邦的浦那)进行的一项调查涵盖了 49 个疫苗储存点、34 个基层医疗中心和 34 个外展点,收集了 2016 年和 2017 年整整两年的疫苗收据、分发和使用数据。
在 Kangra 区(卡介苗 37.1%、DPT 32.1%、麻疹 32.2%、OPV 50.8%、TT 34.1%和五联疫苗 18.4%),几乎所有疫苗的总体浪费率都高于浦那区(卡介苗 35.1%、DPT 25.4%、麻疹 21.7%、OPV 14.3%、TT 23.1%和五联疫苗 13.2%)。Kangra 区的肺炎球菌结合疫苗和麻疹-风疹疫苗的浪费率分别为 27%和 40.5%。随着轮状病毒疫苗从小瓶(5 剂)向小瓶(10 剂)的转变,Kangra 和浦那地区的疫苗储存点的浪费量都增加了(Kangra 从 29%增加到 33.2%,浦那从 17.8%增加到 25.7%)。随着脊髓灰质炎疫苗从肌内注射向皮内注射的转变,Kangra 区的浪费率从 36.1%增加到 54.8%,浦那区的浪费率从 18.4%增加到 26.9%。
几个疫苗的观察到的疫苗浪费率高于预测的方案假设。观察到的疫苗浪费变化表明,印度需要进行基于州或地区的记录和监测,以采取适当的方案行动。