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经皮电刺激治疗顽固性疼痛(作者译)

[The treatment of intractable pain by transdermal electrostimulation (author's transl)].

作者信息

Jenkner F L

出版信息

Wien Klin Wochenschr. 1977 Feb 10;89(4):126-31.

PMID:299970
Abstract

Various kinds of electric currents were examined with regard to their efficacy in the relief of pain when applied transdermally. The most suitable form of current was applied to 39 cases (who had been especially selected in a negative sense) suffering from intractable pain. About half were patients with malignant disease encroaching or causing pressure on nerves or plexuses. The other half consisted of patients suffering from intractable neuralgia totally resistant to all forms of therapy. A diagram of the pulsating direct current is shown. Results were as follows: no effect in nine cases; 5 cases obtained moderate relief of pain for up to 12 hours; the remaining 25 patients reported complete relief of pain already after the first application of current lasting from 12 hours to 3 weeks and--after a series of sessions (3 to 17 treatments)--of up to 12 months. Two of these patients were supplied with a unit for home treatment after their relatives had been trained in the use of the instrument. In these two cases, however, a large number of treatment sessions became necessary. These results warrant continued study of cases of this kind and call for a study of the basic mechanisms possibly underlying these effects. If the present results are confirmed, it is planned to introduce battery-powered miniaturized sets, which patients may use themselves after fixation of electrodes.

摘要

对各种电流经皮给药时缓解疼痛的效果进行了研究。将最合适的电流形式应用于39例(经过特别负面筛选)患有顽固性疼痛的患者。大约一半是患有恶性疾病侵犯或压迫神经或神经丛的患者。另一半由对所有治疗形式完全耐药的顽固性神经痛患者组成。展示了脉动直流电的图表。结果如下:9例无效;5例疼痛得到中度缓解,持续长达12小时;其余25例患者在首次通电后12小时至3周内疼痛完全缓解,经过一系列疗程(3至17次治疗)后,缓解时间长达12个月。其中两名患者在其亲属接受仪器使用培训后,配备了家用治疗仪。然而,在这两个案例中,需要进行大量的治疗疗程。这些结果值得对这类病例继续进行研究,并需要研究这些效果可能潜在的基本机制。如果目前的结果得到证实,计划推出电池供电的小型设备,患者在固定电极后可以自行使用。

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