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对一名以右心室为主的心脏结节病患者进行皮质类固醇治疗的心电图反应的系列观察。

Serial observation of electrocardiographic responses to corticosteroid therapy in a patient with right ventricular-predominant cardiac sarcoidosis.

作者信息

Toh Hiroyuki, Mori Shumpei, Keno Marika, Yokota Shun, Shinkura Yuto, Izawa Yu, Nagamatsu Yuichi, Shimoyama Shinsuke, Fukuzawa Koji, Doi Tomofumi, Hirata Ken-Ichi

机构信息

Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan.

Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan.

出版信息

J Electrocardiol. 2018 Jul-Aug;51(4):658-662. doi: 10.1016/j.jelectrocard.2018.04.008. Epub 2018 Apr 11.

DOI:10.1016/j.jelectrocard.2018.04.008
PMID:29997007
Abstract

Predominant or isolated right ventricular involvement in cardiac sarcoidosis is uncommon, but should always be considered in a case of right ventricular hypertrophy combined with ventricular arrhythmia and/or conduction disturbance. Although improvement in right ventricular hypertrophy and atrioventricular conduction disturbance following corticosteroid therapy has been reported, the detailed serial electrocardiographic responses during corticosteroid therapy, as well as temporal changes in the electrocardiographic, biochemical, and morphological responses, have not been reported. We describe the clinical course and supportive imaging findings of reversible right ventricular hypertrophy and cardiac conduction disturbance in a case of right ventricular-predominant cardiac sarcoidosis.

摘要

心脏结节病以右心室受累为主或孤立出现并不常见,但在右心室肥厚合并室性心律失常和/或传导障碍的病例中应始终予以考虑。尽管已有报道称皮质类固醇治疗后右心室肥厚和房室传导障碍有所改善,但皮质类固醇治疗期间详细的系列心电图反应,以及心电图、生化和形态学反应的时间变化尚未见报道。我们描述了一例以右心室为主的心脏结节病患者可逆性右心室肥厚和心脏传导障碍的临床过程及支持性影像学表现。

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引用本文的文献

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Long-Term Corticosteroid-Sparing Immunosuppression for Cardiac Sarcoidosis.心脏结节病的长期皮质类固醇免疫抑制治疗。
J Am Heart Assoc. 2019 Sep 17;8(18):e010952. doi: 10.1161/JAHA.118.010952. Epub 2019 Sep 6.