Huang Mu-Yang, Zhang Le-Le, Ding Jian, Lu Jin-Jian
State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 7014, N22, Avenida da Universidade, Taipa, Macao China.
2Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Chin Med. 2018 Jul 4;13:35. doi: 10.1186/s13020-018-0192-y. eCollection 2018.
Cancer is still presenting a serious threat to human health worldwide. The understanding of the complex biology of cancer and the development of oncotherapy have led to increasing treatment approaches such as targeted therapy and immunotherapy. Chinese medicinal herbs have attracted considerable attention due to their potential anticancer effects. Some natural products or formulae from Chinese medicinal herbs with directly or indirectly anticancer effects have been reported. In this article, we summarized the current progression on development of anticancer drugs from Chinese medicinal herbs, toward providing ideas for further development and application of Chinese medicinal herbs in cancer therapy.
癌症在全球范围内仍对人类健康构成严重威胁。对癌症复杂生物学的理解以及肿瘤治疗方法的发展，催生了越来越多的治疗手段，如靶向治疗和免疫治疗。中草药因其潜在的抗癌作用而备受关注。一些具有直接或间接抗癌作用的中草药天然产物或配方已见报道。在本文中，我们总结了中草药抗癌药物研发的当前进展，旨在为中草药在癌症治疗中的进一步开发和应用提供思路。
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