一种近红外区域高荧光开启探针，用于血清基质中白蛋白的定量分析。
A highly fluorescent turn-on probe in the near-infrared region for albumin quantification in serum matrix.
机构信息
Laser & Plasma Technology Division, Bhabha Atomic Research Centre, Mumbai 400085, India.
出版信息
Chem Commun (Camb). 2018 Jul 24;54(60):8383-8386. doi: 10.1039/c8cc05058a.
PMID:29998271
Abstract
Developing sensitive and selective near-infrared fluorescent bio-probes for serum albumin detection is an ambitious and highly rewarding task. Herein, we report a styryl based fluorophore for serum albumin detection, which displays an exceptional turn-on emission enhancement of ∼500 fold, the highest reported so far in the near-infrared region, and more importantly enables quantification of albumin in the complex serum matrix.
摘要
开发用于血清白蛋白检测的灵敏和选择性近红外荧光生物探针是一项富有挑战性和高回报的任务。在此，我们报道了一种基于苯乙烯的荧光团，用于血清白蛋白检测，其表现出异常的开启式发射增强约 500 倍，这是迄今为止在近红外区域报道的最高值，更重要的是，它能够在复杂的血清基质中定量白蛋白。
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