Atag Elif, Mutlay Feyza, Soysal Pinar, Semiz Huseyin S, Kazaz Seher N, Keser Murat, Ellidokuz Hulya, Karaoglu Aziz
Department of Medical Oncology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Department of Internal Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Psychogeriatrics. 2018 Sep;18(5):365-370. doi: 10.1111/psyg.12329. Epub 2018 Jul 11.
Depression is one of the most prevalent causes of distress in the geriatric population. The purpose of this study was to examine the prevalence of depressive symptoms in elderly cancer patients and to determine the possible associated factors.
Cancer patients 65 years or older and on active chemotherapy completed the Yesavage Geriatric Depression Scale. We examined the relationship of depressive symptoms with age, gender, marital status, educational background, type of cancer, stage of disease, comorbidities, types of treatment for cancer, the duration after diagnosis of cancer, social support, and pain status.
The study included 170 patients with a mean age of 71 years, and 47.1% were women. The prevalence of a high depressive symptom score was 19.4%. Of the patients who had a high depressive symptom score based on the Yesavage Geriatric Depression Scale, 18.2% had already been diagnosed with depression and used antidepressants. The mean pain score was significantly higher in patients who had a high depressive symptom score compared to others (P = 0.012).
The prevalence of depressive symptoms in elderly cancer patients receiving chemotherapy was similar to that in the geriatric population without cancer. It was also consistent with previous studies on elderly cancer population. Pain was found to be a factor related to depressive symptoms. The prevalence of depression may be reduced by pain control. The treatment of depression may both improve the patient's quality of life and enhance their compliance with treatment.
抑郁症是老年人群中最常见的痛苦原因之一。本研究的目的是调查老年癌症患者抑郁症状的患病率，并确定可能的相关因素。
65岁及以上正在接受积极化疗的癌症患者完成了耶萨维奇老年抑郁量表。我们研究了抑郁症状与年龄、性别、婚姻状况、教育背景、癌症类型、疾病阶段、合并症、癌症治疗类型、癌症诊断后的持续时间、社会支持和疼痛状况之间的关系。
该研究纳入了170名平均年龄为71岁的患者，其中47.1%为女性。高抑郁症状评分的患病率为19.4%。在根据耶萨维奇老年抑郁量表有高抑郁症状评分的患者中，18.2%已被诊断为抑郁症并使用抗抑郁药。与其他患者相比，有高抑郁症状评分的患者的平均疼痛评分显著更高（P = 0.012）。
接受化疗的老年癌症患者抑郁症状的患病率与无癌症的老年人群相似。这也与先前关于老年癌症人群的研究一致。发现疼痛是与抑郁症状相关的一个因素。通过控制疼痛可能会降低抑郁症的患病率。抑郁症的治疗可能既改善患者的生活质量又提高他们对治疗的依从性。
