School of Stomatology, Shandong University, Jinan, Shandong, China.
Department of Oral and Maxillofacial Surgery, Liaocheng People's Hospital, Liaocheng, Shandong, China.
J Oral Pathol Med. 2018 Oct;47(9):895-899. doi: 10.1111/jop.12764. Epub 2018 Jul 28.
Mucocele of the minor salivary gland is usually caused when the duct is injured, mucus leaks into the tissue space and the mucous gland are obstructed, which lead to cystic lesion formation and dilatation. Currently, there are multiple therapeutic methods available with various outcomes. This study aims to provide clinical evidence of polidocanol sclerotherapy for the treatment of mucocele of the minor salivary gland.
In this study, we injected polidocanol into 112 patients who were diagnosed with mucocele of the minor salivary gland and evaluated the treatment efficacy and safety systematically.
Of the 122 cases, 102 cases were cured, eight cases showed remarkable remission, and two cases had partial remission. No recurrence was found during follow-up, and none of the cases showed an invalid effect, resulting in a total cure rate of 91.07%. No severe side effects were observed during treatment or the follow-up period. No significant difference in efficacy between different genders was found (P = 0.490). Polidocanol sclerotherapy for mucocele on the lower lip was more effective compared to mucocele on the inferior surface of the lingual apex (P = 0.035).
Polidocanol sclerotherapy showed satisfying curative effects for mucocele of the minor salivary gland without causing side effects of anesthesia, trauma, or severe pain.
小唾液腺黏液囊肿通常是由于导管损伤,黏液漏入组织间隙并使黏液腺阻塞,导致囊性病变形成和扩张。目前,有多种治疗方法,其结果也各不相同。本研究旨在为聚多卡醇硬化疗法治疗小唾液腺黏液囊肿提供临床证据。
本研究对 112 例被诊断为小唾液腺黏液囊肿的患者注射聚多卡醇,并系统评估了治疗效果和安全性。
122 例患者中,治愈 102 例,显效 8 例,部分缓解 2 例。随访无复发,无无效病例,总有效率为 91.07%。治疗及随访期间无严重不良反应。不同性别疗效差异无统计学意义(P=0.490)。下唇黏液囊肿的疗效优于舌前下极黏液囊肿(P=0.035)。
聚多卡醇硬化疗法治疗小唾液腺黏液囊肿疗效满意,无麻醉、创伤或剧烈疼痛等不良反应。