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涉及小脑后下动脉的破裂椎动脉夹层动脉瘤的血流改变疗法

Flow Alteration Therapy for Ruptured Vertebral Artery Dissecting Aneurysms Involving the Posterior Inferior Cerebellar Artery.

作者信息

Kanematsu Yasuhisa, Satomi Junichiro, Korai Masaaki, Okazaki Toshiyuki, Yamaguchi Izumi, Tada Yoshiteru, Uno Masaaki, Nagahiro Shinji, Takagi Yasushi

机构信息

Department of Neurosurgery, Tokushima University.

Department of Neurosurgery, Kawasaki Medical School.

出版信息

Neurol Med Chir (Tokyo). 2018 Aug 15;58(8):341-349. doi: 10.2176/nmc.oa.2018-0076. Epub 2018 Jul 12.

Abstract

Surgery for- and endovascular treatment of vertebral artery (VA) dissecting aneurysms involving the origin of the posterior inferior cerebellar artery (PICA) remain challenging. Their ideal treatment is complete isolation of the aneurysm by surgical or endovascular trapping plus PICA reconstruction. However, postoperative lower cranial nerve palsy and medullary infarction are potential complications. We report four patients with VA dissecting aneurysms involving the PICA origin who were treated by occipital artery (OA)-PICA bypass followed by proximal occlusion of the VA and clip ligation of the PICA origin instead of trapping. There were no procedural or ischemic complications. In all patients, angiography performed 2-3 weeks later showed good patency of the bypass graft and complete obliteration of the aneurysm. During the follow-up period ranging from 1 to 14 years, none experienced bleeding. Although retrograde blood flow to the dissecting aneurysm persisted in the absence of trapping, iatrogenic lower cranial nerve injury could be avoided. The decrease in aneurysmal flow might elicit spontaneous thrombosis and prevent aneurysmal rerupture. Our technique might be less invasive than aneurysmal trapping and help to prevent rebleeding.

摘要

涉及小脑后下动脉(PICA)起源的椎动脉(VA)夹层动脉瘤的手术治疗和血管内治疗仍然具有挑战性。其理想的治疗方法是通过手术或血管内栓塞加PICA重建来完全隔离动脉瘤。然而,术后较低颅神经麻痹和延髓梗死是潜在的并发症。我们报告了4例涉及PICA起源的VA夹层动脉瘤患者,他们接受了枕动脉(OA)-PICA搭桥术,随后近端闭塞VA并夹闭PICA起源处而非进行栓塞。没有发生手术或缺血性并发症。在所有患者中,术后2-3周进行的血管造影显示搭桥移植物通畅良好且动脉瘤完全闭塞。在1至14年的随访期内,无一例发生出血。尽管在没有栓塞的情况下夹层动脉瘤仍存在逆行血流,但可避免医源性较低颅神经损伤。动脉瘤血流的减少可能引发自发血栓形成并防止动脉瘤再次破裂。我们的技术可能比动脉瘤栓塞侵入性更小,并有助于防止再出血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca2c/6092607/c0c016e9fb47/nmc-58-341-g001.jpg

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