Most sources consider that mothers receiving antineoplastic therapy should not breastfeed, especially with alkylating agents such as carboplatin.[1] It might be possible to breastfeed safely during intermittent therapy with an appropriate period of breastfeeding abstinence, but the duration of abstinence is not clear. Platinum in milk may increase with repeated courses of chemotherapy and the exact form(s), and toxicity of platinum excreted into breastmilk are also not known. The nursing infant would receive platinum compounds orally rather than intravenously and oral absorption of platinum compounds by infants is not known. It appears that it is not safe to breastfeed after carboplatin chemotherapy, and breastfeeding should probably be discontinued. Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[2] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[3]
大多数资料认为，接受抗肿瘤治疗的母亲不应进行母乳喂养，尤其是使用卡铂等烷化剂时。[1] 在间歇治疗期间，适当暂停一段时间母乳喂养后或许有可能安全地进行母乳喂养，但暂停的时长并不明确。化疗疗程重复时，乳汁中的铂含量可能会增加，且排出到母乳中的铂的确切形式及其毒性也尚不清楚。哺乳婴儿会经口而非静脉接受铂化合物，婴儿对铂化合物的口服吸收情况也不明确。卡铂化疗后进行母乳喂养似乎不安全，可能应该停止母乳喂养。化疗可能会对母乳的正常微生物群和化学组成产生不利影响。[2] 在孕期接受化疗的女性更有可能在哺乳婴儿时遇到困难。[3]
