Information in this record refers to the use of sodium fluoride F 18 as a diagnostic agent. The manufacturer recommends withholding breastfeeding for 24 hours after a diagnostic dose of 300-450 MBq (8 to 12 mCi); however, this time might be longer than necessary given the minimal amount of fluoride that appears in breastmilk. Twenty-four hours is about 10 half-lives of fluoride F 18 and less than 0.01% of the radioactivity administered will remain in the body. The mother can nurse just before administration of the radiopharmaceutical. If the mother has expressed and saved milk prior to the examination, she can feed it to the infant during the period of nursing interruption.[1,2] Mothers concerned about the level of radioactivity in their milk could ask to have it tested at a nuclear medicine facility at their hospital. When the radioactivity is at background levels, they may safely resume breastfeeding. A method for measuring milk radioactivity and determining the time when a mother can safely resume breastfeeding has been published.[3]
本记录中的信息涉及使用氟[18F]化钠作为诊断剂。制造商建议在给予300 - 450 MBq（8至12 mCi）的诊断剂量后停止母乳喂养24小时；然而，鉴于母乳中出现的氟含量极少，这段时间可能比必要的时间更长。24小时约为氟[18F]的10个半衰期，给药的放射性物质残留于体内的量将不到0.01%。母亲可在给予放射性药物之前进行哺乳。如果母亲在检查前已挤出并储存了乳汁，她可以在哺乳中断期间喂给婴儿。[1,2] 担心乳汁中放射性水平的母亲可要求在其医院的核医学科对乳汁进行检测。当放射性处于本底水平时，她们可以安全地恢复母乳喂养。一种测量乳汁放射性并确定母亲可安全恢复母乳喂养时间的方法已发表。[3]
