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氟替卡松,局部用

Fluticasone, Topical

PMID:29999824
Abstract

Topical fluticasone has not been studied during breastfeeding. Since only extensive application of the most potent corticosteroids may cause systemic effects in the mother, it is unlikely that short-term application of topical corticosteroids would pose a risk to the breastfed infant by passage into breastmilk. However, it would be prudent to use the least potent drug on the smallest area of skin possible. It is particularly important to ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Current guidelines allow topical corticosteroids to be applied to the nipples just after nursing for eczema, with the nipples cleaned gently before nursing.[1,2] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]

摘要

外用氟替卡松在哺乳期尚未进行研究。由于只有广泛应用最强效的皮质类固醇才可能对母亲产生全身影响,因此外用皮质类固醇短期应用不太可能通过进入母乳而对母乳喂养的婴儿构成风险。然而,谨慎的做法是在尽可能小的皮肤区域使用效力最低的药物。特别重要的是要确保婴儿皮肤不与已治疗的皮肤区域直接接触。当前指南允许在哺乳后立即将外用皮质类固醇用于乳头治疗湿疹,在哺乳前轻轻清洁乳头。[1,2] 仅应将水溶性乳膏或凝胶产品用于乳房,因为软膏可能会使婴儿通过舔舐接触到高剂量的矿物石蜡。[3]

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