No information is available on the clinical use of secnidazole during breastfeeding and no studies have evaluated adverse effects of secnidazole on the infant during breastfeeding, but presumably they are similar to those of the closely related drug, metronidazole, such as increased risk of oral and rectal infections. As with metronidazole, concern has been raised about exposure of healthy infants to secnidazole via breastmilk, because of possible mutagenicity and carcinogenicity. Based on the elimination half-life of secnidazole of approximately 17 hours, the manufacturer recommends avoidance of breastfeeding for 96 after a single dose. Other drugs are available for bacterial vaginosis, and can be given vaginally, which should result in lower amounts in breastmilk.
关于塞克硝唑在母乳喂养期间的临床应用尚无可用信息，也没有研究评估塞克硝唑在母乳喂养期间对婴儿的不良反应，但据推测，这些不良反应与密切相关的药物甲硝唑相似，如口腔和直肠感染风险增加。与甲硝唑一样，由于可能存在致突变性和致癌性，健康婴儿通过母乳接触塞克硝唑的问题也引起了关注。基于塞克硝唑约17小时的消除半衰期，制造商建议单次给药后96小时内避免母乳喂养。细菌性阴道病有其他药物可供选择，且可经阴道给药，这应会使母乳中的药物含量降低。
