Amounts of tinidazole in milk are less than doses given to infants. Measurements of infant plasma levels during breastfeeding have not been reported. No studies have evaluated adverse effects of tinidazole on the infant during breastfeeding, but presumably they are similar to those of the closely related drug, metronidazole, such as increased risk of oral and rectal infections. As with metronidazole, concern has been raised about exposure of healthy infants to tinidazole via breastmilk,[1] because of possible mutagenicity and carcinogenicity. Opinions vary among experts on the advisability of using tinidazole during longer-term therapy while breastfeeding, but avoidance of breastfeeding for 3 days after a single dose should allow milk levels to drop to negligible values.[2] Other drugs are available for bacterial vaginosis, and can be given vaginally, which should result in lower amounts in breastmilk.
牛奶中的替硝唑含量低于给予婴儿的剂量。尚未有关于母乳喂养期间婴儿血浆水平测量的报道。尚无研究评估替硝唑在母乳喂养期间对婴儿的不良影响，但推测其与密切相关药物甲硝唑的影响相似，如口腔和直肠感染风险增加。与甲硝唑一样，由于可能的致突变性和致癌性，健康婴儿通过母乳接触替硝唑引发了关注。[1] 专家们对于母乳喂养期间长期治疗时使用替硝唑的 advisability 意见不一，但单次给药后避免母乳喂养 3 天应可使母乳中的水平降至可忽略不计的值。[2] 细菌性阴道病有其他可用药物，可经阴道给药，这应会使母乳中的含量更低。
