Alclometasone has not been studied during breastfeeding. Since only extensive application of the most potent of these drugs cause systemic effects in the mother, it is unlikely that short-term application of topical corticosteroids would pose a risk to the breastfed infant by passage into breastmilk. However, it would be prudent to use the least potent drug on the smallest area of skin possible. It is particularly important to ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only the lower potency corticosteroids (e.g., hydrocortisone, triamcinolone) should be used on the nipple or areola where the infant could directly ingest the drugs from the skin. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1] Any topical corticosteroid should be wiped off thoroughly prior to nursing if it is being applied to the breast or nipple area.
尚未对阿氯米松在哺乳期的情况进行研究。由于只有这些药物中最强效的药物广泛应用才会在母亲体内产生全身作用,因此局部使用皮质类固醇短期应用不太可能因进入母乳而对母乳喂养的婴儿构成风险。然而,谨慎的做法是在尽可能小的皮肤区域使用效力最低的药物。特别重要的是要确保婴儿的皮肤不与已治疗的皮肤区域直接接触。仅应在婴儿可能直接从皮肤上摄入药物的乳头或乳晕上使用低效力的皮质类固醇(如氢化可的松、曲安奈德)。仅应将与水混溶的乳膏或凝胶产品涂抹于乳房,因为软膏可能会使婴儿通过舔舐接触到高含量的矿物石蜡。[1] 如果将任何局部皮质类固醇应用于乳房或乳头区域,在哺乳前应彻底擦拭干净。