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氟轻松

Fluocinolone

PMID:29999780
Abstract

Fluocinolone has not been studied during breastfeeding. Since only extensive application of the most potent corticosteroids may cause systemic effects in the mother, it is unlikely that short-term application of topical corticosteroids would pose a risk to the breastfed infant by passage into breastmilk. However, it would be prudent to use the least potent drug on the smallest area of skin possible. It is particularly important to ensure that the infant’s skin does not come into direct contact with the areas of skin that have been treated. Only the lower potency corticosteroids should be used on the nipple or areola where the infant could directly ingest the drugs from the skin. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1] Any topical corticosteroid should be wiped off thoroughly prior to nursing if it is being applied to the breast or nipple area. Maternal use of ear drops, or eye insert that contains fluocinolone presents negligible risk for the nursing infant. Most expert opinion is that fluocinolone acetonide implants can be used for diabetic macular edema in nursing mothers.[2]

摘要

哺乳期使用氟轻松尚未进行研究。由于仅强效皮质类固醇的广泛应用可能会对母亲产生全身影响,短期外用皮质类固醇不太可能通过进入母乳而对母乳喂养的婴儿构成风险。然而,谨慎的做法是在尽可能小的皮肤区域使用效力最低的药物。特别重要的是要确保婴儿皮肤不直接接触已治疗的皮肤区域。仅应在婴儿可能直接从皮肤上摄入药物的乳头或乳晕上使用低效力的皮质类固醇。仅应将与水混溶的乳膏或凝胶产品涂于乳房,因为软膏可能会使婴儿通过舔舐接触到高浓度的矿物石蜡。[1]如果将任何外用皮质类固醇涂于乳房或乳头区域,在哺乳前应彻底擦拭干净。母亲使用含氟轻松的耳滴剂或眼用植入剂对哺乳婴儿的风险可忽略不计。大多数专家意见认为,醋酸氟轻松植入剂可用于哺乳期母亲的糖尿病性黄斑水肿。[2]