No relevant published information exists on the use of fluvastatin during breastfeeding. Because of a concern with disruption of infant lipid metabolism, the consensus is that fluvastatin should not be used during breastfeeding. However, others have argued that children homozygous for familial hypercholesterolemia are treated with statins beginning at 1 year of age, that statins have low oral bioavailability, and risks to the breastfed infant are low, especially with rosuvastatin and pravastatin.[1] Until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
关于哺乳期使用氟伐他汀，尚无相关的公开信息。由于担心会干扰婴儿的脂质代谢，目前的共识是哺乳期不应使用氟伐他汀。然而，也有其他人认为，患有家族性高胆固醇血症的纯合子儿童从1岁起就开始使用他汀类药物治疗，他汀类药物的口服生物利用度低，对母乳喂养婴儿的风险较低，尤其是瑞舒伐他汀和普伐他汀。[1] 在获得更多数据之前，可能更倾向于使用替代药物，尤其是在哺育新生儿或早产儿期间。
Zotero 插件