Topical azelaic acid has not been studied during breastfeeding. Because only 4% of a dose is absorbed after topical application and it is a chemical that appears in foods, bloodstream and breastmilk normally, azelaic acid is considered a low risk to the nursing infant.[1-3] If azelaic acid is required by the mother, it is not a reason to discontinue breastfeeding. Do not apply azelaic acid to the breast or nipple and ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[4]
外用壬二酸在哺乳期尚未进行研究。由于外用后仅4%的剂量会被吸收，且它是一种通常存在于食物、血液和母乳中的化学物质，因此壬二酸被认为对哺乳婴儿风险较低。[1-3] 如果母亲需要使用壬二酸，这不是停止母乳喂养的理由。请勿将壬二酸涂抹于乳房或乳头，并确保婴儿皮肤不与已治疗的皮肤区域直接接触。仅应将水溶性乳膏或凝胶产品涂抹于乳房，因为软膏可能会使婴儿通过舔舐接触到高含量的矿物石蜡。[4]
