Fusidic acid is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries as topical and systemic dosage forms. Data on excretion of fusidic acid into breastmilk are quite old and not from a well-designed study, but levels in breastmilk after intravenous fusidic acid appear to be low. With topical products, ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1] Fusidic acid applied topically to the nipples appears to be relatively ineffective as a treatment for sore, cracked nipples.
夫西地酸未被美国食品药品监督管理局批准在美国上市，但在其他国家有局部和全身剂型。关于夫西地酸排泄到母乳中的数据非常陈旧，并非来自设计良好的研究，但静脉注射夫西地酸后母乳中的含量似乎较低。使用局部产品时，要确保婴儿皮肤不与已治疗的皮肤区域直接接触。仅应将水溶性乳膏或凝胶产品涂抹于乳房，因为软膏可能会使婴儿通过舔舐接触到高含量的矿物石蜡。[1] 局部应用于乳头的夫西地酸作为治疗乳头疼痛、皲裂的方法似乎效果相对不佳。
