Clarke B E, Xipell J M, Thomas D P
Am J Surg Pathol. 1985 Nov;9(11):806-15. doi: 10.1097/00000478-198511000-00004.
The clinical, radiologic, and pathological features of eight cases of fibrohistiocytic bone lesions histologically identical to the nonossifying fibroma of childhood are presented. They differed from the childhood lesion in their clinical and radiological features. They occurred in adults, and were frequently associated with pain in the absence of complicating fracture. They were not confined to the metaphysis of long bones. When metaphyseal, the lesions also frequently showed a tendency to involve the epiphysis. Others occurred in the diaphysis of long bones, in the pelvis, and in a rib. Three recurred locally, but none has metastasized. Other fibrohistiocytic and fibroblastic tumours of bone, including malignant fibrous histiocytoma, giant cell tumour, fibrosarcoma, and desmoplastic fibroma can be differentiated on radiological and histological features, and hyperparathyroidism may need to be excluded by biochemical investigations.
本文报告了8例组织学上与儿童非骨化性纤维瘤相同的纤维组织细胞性骨病变的临床、放射学及病理学特征。它们在临床和放射学特征上与儿童病变不同。这些病变发生于成年人,在无骨折并发症时常常伴有疼痛。它们并不局限于长骨的干骺端。当位于干骺端时,病变也常常有累及骨骺的倾向。其他病变发生于长骨骨干、骨盆及肋骨。3例出现局部复发,但均未发生转移。骨的其他纤维组织细胞性和纤维母细胞性肿瘤,包括恶性纤维组织细胞瘤、骨巨细胞瘤、纤维肉瘤及促纤维组织增生性纤维瘤,可根据放射学和组织学特征进行鉴别,可能需要通过生化检查排除甲状旁腺功能亢进。