Stathopoulos G, Papamichail M, Holborow E J, Davies A J
Br J Exp Pathol. 1977 Feb;58(1):95-100.
The lymph node cell populations from 24 patients with non-Hodgkin's lymphoma were investigated for some of the surface characteristics which are used as T- and B-lymphocyte markers. Nineteen of the patients had had no treatment of any kind while the other 5 had had either recent radiotherapy or chemotherapy. Seven lymph nodes from patients without malignant disease and 7 others with reactive changes were also studied. It was found that lymphocytic lymphomas, nodular or diffuse, well or poorly differentiated, had a high proportion of cells which were positive for B-cell markers. Other non-lymphocytic lymphomas had a higher proportion of cells positive for T-cell markers, and were similar to the cells from non-malignant lymph nodes.
对24例非霍奇金淋巴瘤患者的淋巴结细胞群进行了研究,以检测一些用作T淋巴细胞和B淋巴细胞标志物的表面特征。其中19例患者未曾接受过任何治疗,另外5例患者近期接受过放疗或化疗。还研究了7例无恶性疾病患者的淋巴结以及7例有反应性改变患者的淋巴结。结果发现,结节性或弥漫性、高分化或低分化的淋巴细胞性淋巴瘤,其B细胞标志物阳性的细胞比例较高。其他非淋巴细胞性淋巴瘤,T细胞标志物阳性的细胞比例较高,且与非恶性淋巴结的细胞相似。