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一名具有典型川崎病体征的发热婴儿冠状动脉受累的极早期发展与识别

Very Early Development and Recognition of Coronary Involvement in a Febrile Infant with Typical Signs of Kawasaki Disease.

作者信息

Buonsenso D, Cristaldi S, Reale A, de Jacobis I Tarissi, Granata L, Marchesi A

机构信息

Pediatric Emergency Department, Bambino Gesù Children's Hospital, Institute for Research and Health Care (IRCCS), Rome, Italy.

Pediatric and Infectious Disease Unit, Bambino Gesù Children's Hospital, Institute for Research and Health Care (IRCCS), Rome, Italy.

出版信息

Mediterr J Hematol Infect Dis. 2018 Jun 20;10(1):e2018037. doi: 10.4084/MJHID.2018.037. eCollection 2018.

Abstract

Kawasaki disease (KD) is an acute, self-limited, inflammatory disease affecting medium-sized arteries and particularly the coronary arteries in about 25% of untreated cases. KD is a clinical diagnosis based on the presence of ≥5 days of fever and the presence of ≥4 of the 5 principal clinical criteria. We described, for the first time to our knowledge, a case of a very early development (on day 1) of typical KD with transient coronary involvement, diagnosed on day 2 of disease and treated with aspirin and steroids on day 3, with complete resolution of clinical signs and coronary involvement.

摘要

川崎病(KD)是一种急性、自限性炎症性疾病,可累及中等大小动脉,在约25%未经治疗的病例中尤其会累及冠状动脉。KD是一种基于发热≥5天以及5项主要临床标准中存在≥4项来做出的临床诊断。据我们所知,我们首次描述了一例典型KD极早期(第1天)发病且伴有短暂性冠状动脉受累的病例,该病例在疾病第2天确诊,并于第3天接受阿司匹林和类固醇治疗,临床症状和冠状动脉受累完全消退。

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本文引用的文献

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Asymptomatic Kawasaki Disease in a 3-Month-Old Infant.一名3个月大婴儿的无症状川崎病
Pediatrics. 2016 Aug;138(2). doi: 10.1542/peds.2015-3936. Epub 2016 Jul 1.
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Intravenous immunoglobulin, pharmacogenomics, and Kawasaki disease.静脉注射免疫球蛋白、药物基因组学与川崎病。
J Microbiol Immunol Infect. 2016 Feb;49(1):1-7. doi: 10.1016/j.jmii.2014.11.001. Epub 2014 Nov 11.
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Kawasaki syndrome and concurrent Coxsackie virus B3 infection.川崎病合并柯萨奇病毒 B3 感染。
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