A new crystal form and anti-microbial activity of ()-1-[3-(2-hy-droxy-benzyl-idene-amino)-phen-yl]ethanone.

The title Schiff base compound, CHNO, crystallizes in a new crystal form in the space group 222, which is different from the monoclinic 2/ space group reported previously [De (2009 ▸). , , 595-598]. An intra-molecular O-H⋯N hydrogen bond occurs between the hy-droxy and azomethine moieties. In the crystal, mol-ecules are linked by weak C-H⋯O hydrogen bonds into supra-molecular chains propagating along the -axis direction with a (8) graph-set motif. The contribution of these two contacts in Hirshfeld surface area are around 19 and 21%, respectively. The title compound was screened for its anti-bacterial activity against two gram-negative ( and ) and one gram-positive ( bacteria. The results of this study reveal that this Schiff base shows good activity against only one bacterium, .