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-[(2-羟基萘-1-基)(3-甲基苯基)甲基]乙酰胺的晶体结构和 Hirshfeld 表面分析

Crystal structure and Hirshfeld surface analysis of -[(2-hy-droxy-naphthalen-1-yl)(3-methyl-phen-yl)meth-yl]acetamide.

作者信息

Boudebbous Khawla, Zemamouche Wissem, Debache Abdelmadjid, Hamdouni Noudjoud, Boudjada Ali

机构信息

Laboratoire de Synthèse de Molécules, d'Intérêts Biologiques, Département de Chimie, Université Mentouri-Constantine, 25000 Constantine, Algeria.

Laboratoire de Cristallographie, Département de Physique, Université Mentouri-Constantine, 25000 Constantine, Algeria.

出版信息

Acta Crystallogr E Crystallogr Commun. 2018 Jun 21;74(Pt 7):1002-1005. doi: 10.1107/S2056989018008423. eCollection 2018 Jul 1.

Abstract

The title compound, CHNO, is of inter-est as a precursor to biologically active substituted quinolines and related compounds. This compound crystallizes with two independent mol-ecules ( and ) in the asymmetric unit. The dihedral angles between mean planes of the methyl-phenyl ring and the naphthalene ring system are 78.32 (6) and 84.70 (6)° in mol-ecules and , respectively. In the crystal, the anti-ferroelectric packing of mol-ecules and is of an type along the -axis direction. The crystal structure features N-H⋯O, O-H⋯O and weak C-H⋯O hydrogen bonds, which link the mol-ecules into infinite chains propagating along the -axis direction.

摘要

标题化合物CHNO作为生物活性取代喹啉及相关化合物的前体具有重要意义。该化合物在不对称单元中结晶出两个独立的分子(和)。在分子和中,甲基苯环与萘环体系平均平面之间的二面角分别为78.32 (6)°和84.70 (6)°。在晶体中,分子和沿轴方向呈反铁电堆积,属于型。晶体结构具有N-H⋯O、O-H⋯O和弱C-H⋯O氢键,这些氢键将分子连接成沿轴方向延伸的无限链。

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