Simon D, Kampylafka E, Hueber A J
Medizinische Klinik 3, Rheumatologie und Immunologie, Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Deutschland.
Z Rheumatol. 2018 Nov;77(9):776-782. doi: 10.1007/s00393-018-0503-9.
The complex pathogenesis of psoriatic arthritis (PsA) is still only partially understood; however, recently a greatly improved understanding of this disease has been achieved, especially with respect to the inflammatory processes of the entheses. Thus, the clinical aspects of enthesitis increasingly differentiate PsA from other autoimmune diseases and sharpen the unique pathological clinical picture of PsA. Better pathophysiological understanding and the development of different biomarker approaches will bolster early detection of PsA. Therefore, the successful early recognition of PsA and more reliable identification of psoriasis patients at risk might be possible in the near future.
银屑病关节炎（PsA）复杂的发病机制目前仍只得到部分理解；然而，最近人们对这种疾病的认识有了很大提高，特别是在附着点炎的炎症过程方面。因此，附着点炎的临床特征越来越使PsA与其他自身免疫性疾病区分开来，并凸显出PsA独特的病理临床特征。对病理生理学的更好理解以及不同生物标志物方法的发展将有助于PsA的早期检测。因此，在不久的将来，成功早期识别PsA并更可靠地识别有风险的银屑病患者或许是可能的。
