实验性异位移植后骨膜细胞成骨的特点

Peculiarities of Osteogenesis by Periosteal Cells after Experimental Ectopic Transplantation.

作者信息

Ivanov A A, Danilova T I, Popova O P, Erohin A I, Semenihina E S

机构信息

I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Moscow, Russia.

出版信息

Bull Exp Biol Med. 2018 Jul;165(3):408-411. doi: 10.1007/s10517-018-4181-z. Epub 2018 Jul 12.

DOI:10.1007/s10517-018-4181-z

PMID:30003422

Abstract

We carried out a comparative study of the features of osteogenesis from the progenitor osteogenic periosteal cells in rabbit and human. At the initial stages, high osteogenic potential of both human and rabbit periosteal cells was observed. However, at the later stages, the cell response favors resorption of the new bone tissue formed from periosteal cells in rabbits, but does not affect the bone tissue formed from human progenitor osteogenic periosteal cells. These functional characteristics of rabbit periosteal cells should be considered when planning the experiment.

摘要

我们对兔和人成骨祖细胞的成骨特征进行了对比研究。在初始阶段，观察到人和兔骨膜细胞均具有较高的成骨潜力。然而，在后期阶段，细胞反应有利于兔骨膜细胞形成的新骨组织的吸收，但不影响人成骨祖细胞形成的骨组织。在设计实验时应考虑兔骨膜细胞的这些功能特性。