Hospital Universitário Onofre Lopes, Federal University of Rio Grande do Norte, Natal, Brazil.
Department of Integrative Medicine, Federal University of Rio Grande do Norte, Natal, Brazil.
Acta Neurol Scand. 2018 Nov;138(5):459-462. doi: 10.1111/ane.12995. Epub 2018 Jul 12.
The Erasmus Guillain Barre Outcome Score (EGOS) is a prognostic model that predicts the chance of being able to walk independently at 6 months after Guillain Barré syndrome (GBS). This study was conducted aiming to determine the validity of EGOS in a Brazilian population.
Data collected from GBS patients in Rio Grande do Norte, Brazil, were used to determine the validity of EGOS. GBS disability score was assessed in the second week of disease and at 6 months.
A total of 206 subjects were studied. The Brazilian patients were younger, with a more severe clinical presentation, with higher percentage of cranial nerve involvement and upper respiratory infection. There was no difference relative to sex or presence of anti-gangliosides antibodies. The demyelinating variant was more common (73.9%). However, only 24% of the Brazilians with EGOS 5.5-7 were not able to walk after 6 months, compared to 52% to European Group. Nine patients (3.8%) presented nodopathies, of these four had an EGOS >5, but only one of the latter group was unable to walk after 6 months of GBS.
Erasmus Guillain Barre Outcome Score was not a good predictor for the ability to walk after 6 months of GBS in Rio Grande do Norte, Brazil. Differences could be that the Brazilian GBS were younger, or alternatively, it could be due to a different infection profile or in the incidence of nodopathies.
爱拉斯谟·吉兰-巴雷结局评分(EGOS)是一种预测吉兰-巴雷综合征(GBS)后 6 个月独立行走能力的预后模型。本研究旨在确定 EGOS 在巴西人群中的有效性。
从巴西北里奥格兰德州的 GBS 患者中收集数据,以确定 EGOS 的有效性。GBS 残疾评分在疾病的第二周和 6 个月时进行评估。
共研究了 206 名患者。巴西患者年龄较小,临床表现更严重,颅神经受累和上呼吸道感染的比例更高。性别或抗神经节苷脂抗体的存在无差异。脱髓鞘变异更为常见(73.9%)。然而,与欧洲组相比,只有 24%的 EGOS 为 5.5-7 的巴西患者在 6 个月后无法行走,而 9 名患者(3.8%)出现结节病,其中 4 名 EGOS >5,但在后者中只有 1 名患者在 GBS 后 6 个月无法行走。
在巴西北里奥格兰德州,爱拉斯谟·吉兰-巴雷结局评分对 GBS 后 6 个月的行走能力不是一个很好的预测指标。差异可能是巴西 GBS 患者年龄较小,或者可能是由于不同的感染谱或结节病的发病率不同。