个性化医疗的基础是生物样本库的建立及其标准化。
The foundation of personalized medicine is the establishment of biobanks and their standardization.
作者信息
Policiuc Liliana, Buse Mihail, Gulei Diana, Andreea Zimta Alina, Braicu Cornelia, Iulia Irimie Alexandra, Berindan-Neagoe Ioana
机构信息
Research Center for Functional Genomics and Translational Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
出版信息
J BUON. 2018 May-Jun;23(3):550-560.
The present review outlines the current information available about biobanks including: summarizing the main ethical issues encountered when integrating patient samples in research projects; emphasizing the importance of biobanks as the basis for any personalized medicine therapies in cancer with a particular focus for oral cancer, through the use of biomarkers; and providing examples of biobanks that use anonymous sample collection and labelling methodologies to help alleviate the problems of privacy, informed consent, data security as well as public trust.
本综述概述了目前关于生物样本库的可用信息，包括：总结在研究项目中整合患者样本时遇到的主要伦理问题；强调生物样本库作为癌症个性化医疗（尤其关注口腔癌）基础的重要性，通过使用生物标志物来实现；并提供一些生物样本库的实例，这些生物样本库采用匿名样本采集和标记方法，以帮助缓解隐私、知情同意、数据安全以及公众信任等问题。
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