Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil.
J Periodontol. 2018 Dec;89(12):1383-1389. doi: 10.1002/JPER.17-0710. Epub 2018 Aug 29.
This study aimed to compare the periodontal status of liver transplant candidates (LTCs) with healthy controls.
Fifty liver transplant candidates (LTC group) and fifty patients without liver disease (control group) underwent a complete periodontal examination. The groups were matched according to sex, age, and smoking status. A structured questionnaire was applied to record demographic data, systemic health, and information related to liver disease. Full-mouth complete periodontal examination of six sites per tooth was performed: gingival recession (GR), probing depth (PD), attachment loss (AL), bleeding on probing (BOP), and visible plaque index (VPI). The groups were compared in regard to periodontal clinical variables.
Patients with cirrhosis had greater prevalence of periodontitis than healthy controls (P < 0.001). In addition, they had greater mean percentage of sites with AL ≥3 mm (P = 0.008) and AL ≥5 mm (P = 0.023), greater mean AL (P = 0.003), greater mean gingival recession (P < 0.001), and more missing teeth than in the control group (P = 0.02).
Liver transplant candidates presented greater prevalence, extent, and severity of periodontitis than matched control patients.
本研究旨在比较肝移植候选者(LTC)与健康对照者的牙周状况。
50 名肝移植候选者(LTC 组)和 50 名无肝病患者(对照组)接受了全面的牙周检查。两组根据性别、年龄和吸烟状况相匹配。应用结构化问卷记录人口统计学数据、全身健康状况以及与肝病相关的信息。对每颗牙齿的六个位点进行全口完整牙周检查:牙龈退缩(GR)、探诊深度(PD)、附着丧失(AL)、探诊出血(BOP)和可见菌斑指数(VPI)。比较两组牙周临床变量。
肝硬化患者的牙周炎患病率高于健康对照组(P<0.001)。此外,他们的 AL≥3mm 的位点百分比均值更大(P=0.008)和 AL≥5mm 的位点百分比均值更大(P=0.023),平均附着丧失更大(P=0.003),平均牙龈退缩更大(P<0.001),并且缺失牙数多于对照组(P=0.02)。
与匹配的对照组患者相比,肝移植候选者的牙周炎患病率、程度和严重程度更高。