Hsu Jennifer L, Bhatnagar Udit, Stys Maria, Hoffman Wendell
Department of Internal Medicine, University of South Dakota Sanford School of Medicine.
Sanford Health Infectious Disease, Sioux Falls, South Dakota.
S D Med. 2018 Jun;71(6):246-250.
We present the case of a 64-year-old man with Mycobacterium chimaera prosthetic aortic valve endocarditis likely acquired through exposure to a contaminated heater-cooler device used for cardiopulmonary bypass during valve replacement. This case demonstrates multi-system involvement with a non-tuberculous mycobacterial species that was previously not considered a significant human pathogen. We review the key features of the case and review published literature regarding an international outbreak of M. chimaera arising from point-source contamination during the manufacturing process. This report highlights the importance of clinician awareness of this international outbreak.
我们报告了一例64岁男性患者，其感染了嵌合体分枝杆菌，导致人工主动脉瓣心内膜炎，可能是在瓣膜置换期间接触用于体外循环的受污染热交换器而感染的。该病例显示了一种非结核分枝杆菌对多系统的累及，这种细菌以前不被认为是重要的人类病原体。我们回顾了该病例的关键特征，并查阅了已发表的关于因制造过程中的点源污染而导致嵌合体分枝杆菌国际暴发的文献。本报告强调了临床医生对这一国际暴发事件的认识的重要性。
