Rahimi Hanna, Twilt Marinka, Herlin Troels, Spiegel Lynn, Pedersen Thomas Klit, Küseler Annelise, Stoustrup Peter
Department of Pediatrics, Aarhus University Hospital, Palle Juul-Jensens Boulevard 121, 8200, Aarhus N, Denmark.
Department of Pediatrics, Division of Rheumatology, Alberta Children's Hospital, 2888 Shaganappi Trail NW, Calgary, AB, Canada.
Pediatr Rheumatol Online J. 2018 Jul 13;16(1):47. doi: 10.1186/s12969-018-0259-4.
Little is known about the chronicity of orofacial symptoms and how this influences the oral health-related quality of life in juvenile idiopathic arthritis (JIA). Therefore, our objectives were to study the long-term changes in self-reported orofacial symptoms, and to define the impact of orofacial symptoms on oral health-related quality of life in JIA.
At baseline (T0), 157 consecutive JIA patients ≤20 years completed a patient pain questionnaire that incorporates domains related to the orofacial area. At the 2 year follow-up (T1), 113 patients completed the same questionnaire (response rate 72%) in addition to the Child Perception's Questionnaire; a validated 31-item questionnaire addressing oral health-related quality of life.
At T0, 53% (60/113) of patients reported the presence of orofacial pain, and 36% (41/113) of patients reported compromised orofacial function. At T1, 77% (46/60) of patients with pain at T0 reported persistent pain, and 66% (27/41) of patients with functional disability at T0 reported persistent disability. Patients with orofacial symptoms reported a significantly greater prevalence of negative impact of orofacial conditions on general quality of life and within the domains of emotional and social well-being compared to asymptomatic patients.
Self-reported orofacial pain and functional disability were common findings in a cohort of JIA patients followed over 2 years. These symptoms seem to persist over time in most patients, and have a significant negative impact on oral health-related quality of life.
关于口面部症状的慢性病程以及其如何影响青少年特发性关节炎（JIA）患者的口腔健康相关生活质量，目前所知甚少。因此，我们的目标是研究自我报告的口面部症状的长期变化，并确定口面部症状对JIA患者口腔健康相关生活质量的影响。
在基线时（T0），157名年龄≤20岁的连续JIA患者完成了一份包含口面部区域相关领域的患者疼痛问卷。在2年随访时（T1），113名患者除完成相同问卷（应答率72%）外，还完成了儿童感知问卷；这是一份经过验证的31项问卷，用于评估口腔健康相关生活质量。
在T0时，53%（60/113）的患者报告存在口面部疼痛，36%（41/113）的患者报告口面部功能受损。在T1时，T0时疼痛的患者中有77%（46/60）报告疼痛持续存在，T0时存在功能障碍的患者中有66%（27/41）报告功能障碍持续存在。与无症状患者相比，有口面部症状的患者报告口面部状况对总体生活质量以及在情感和社会幸福感领域产生负面影响的患病率显著更高。
在随访2年的JIA患者队列中，自我报告的口面部疼痛和功能障碍是常见现象。这些症状在大多数患者中似乎会随着时间持续存在，并对口腔健康相关生活质量产生重大负面影响。
