Emory University School of Medicine, United States.
University of Southern California, United States.
J Anxiety Disord. 2019 Jan;61:55-63. doi: 10.1016/j.janxdis.2018.06.004. Epub 2018 Jun 18.
This initial feasibility study examined the use of virtual reality exposure therapy (VRE) in the treatment of MST-related PTSD, with newly developed content tailored to MST. Participants included 15 veterans (26% male) with MST-related PTSD. Assessment of PTSD, depression, and psychophysiological indicators of distress occurred at pre-treatment, post-treatment, and 3-month follow-up. Treatment included 6-12 VRE sessions. There were significant reductions in pre- to post-treatment PTSD (CAPS severity: t(10) = 3.69, p = .004; PCL-5: t(10) = 3.79, p = .004) and depressive symptoms, (PHQ-9: t(8) = 2.83, p = .022), which were maintained at follow-up. There also was a significant pre- to post-treatment reduction in heart rate response to a trauma cue. Cohen's d effect sizes were large (CAPS: d = 1.11; PCL-5: d = 1.14, PHQ-9: d = .94), and the percentage of participants meeting PTSD criteria continued to decline from post-treatment (53%) to follow-up (33%). Findings indicate VRE can be safely delivered and is a promising treatment for MST-related PTSD.
这项初步可行性研究探讨了虚拟现实暴露疗法（VRE）在治疗与 MST 相关的 PTSD 中的应用，采用了新开发的针对 MST 的内容。参与者包括 15 名患有与 MST 相关的 PTSD 的退伍军人（26%为男性）。在治疗前、治疗后和 3 个月随访时，评估 PTSD、抑郁和痛苦的心理生理指标。治疗包括 6-12 次 VRE 疗程。与 PTSD（CAPS 严重程度：t(10) = 3.69, p =.004；PCL-5：t(10) = 3.79, p =.004）和抑郁症状（PHQ-9：t(8) = 2.83, p =.022）相关的 PTSD 和抑郁症状均有显著降低，且在随访时仍保持不变。对创伤线索的心率反应也从治疗前到治疗后显著降低。Cohen's d 效应量较大（CAPS：d = 1.11；PCL-5：d = 1.14，PHQ-9：d =.94），且符合 PTSD 标准的参与者比例从治疗后（53%）继续下降到随访时（33%）。研究结果表明，VRE 可以安全实施，并且是治疗与 MST 相关的 PTSD 的一种有前途的治疗方法。
