Department of Oral Diagnosis, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Oral Dis. 2019 Jan;25(1):117-125. doi: 10.1111/odi.12941. Epub 2018 Aug 14.
We analysed the correlation between magnetic resonance images of the parotid and submandibular glands and the salivary flow rate in patients with Sjögren's syndrome.
We retrospectively reviewed magnetic resonance images (heterogeneous signal-intensity distribution and gland volume on T1- and fat-suppressed T2-weighted images, and multiple high-signal-intensity spots on magnetic resonance sialograms in the parotid and submandibular glands) obtained from 66 patients who were diagnosed with Sjögren's syndrome. We evaluated the relationship between these imaging features and their salivary flow rates in stimulated and unstimulated conditions.
We found that as the disease progressed, both the heterogeneous signal-intensity distribution and the volumes of the parotid and the submandibular glands were significantly related to the stimulated and the unstimulated salivary flow rate. These imaging features were more highly correlated in assessments of the submandibular gland than in those of the parotid gland for both stimulated and unstimulated salivary flow rates.
Magnetic resonance image features of heterogeneity and smaller volume in the submandibular gland are reliable for predicting hyposalivation related to the progression of Sjögren's syndrome.
我们分析了干燥综合征患者的腮腺和下颌下腺磁共振成像与唾液流率之间的相关性。
我们回顾性分析了 66 例干燥综合征患者的磁共振图像（T1 和脂肪抑制 T2 加权图像上的不均匀信号强度分布和腺体体积，以及磁共振唾液腺图像上的多个高信号强度点）。我们评估了这些影像学特征与刺激和非刺激条件下唾液流率之间的关系。
我们发现，随着疾病的进展，腮腺和下颌下腺的不均匀信号强度分布和体积均与刺激和非刺激唾液流率显著相关。这些影像学特征在评估刺激和非刺激唾液流率时，在下颌下腺的相关性均高于腮腺。
下颌下腺磁共振图像的异质性和较小体积特征可可靠地预测与干燥综合征进展相关的唾液分泌减少。
