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60至70岁患者胸腰椎不稳定爆裂骨折中联合前后路椎体融合术与混合固定术的比较。

Comparison of combined posterior and anterior spondylodesis versus hybrid stabilization in unstable burst fractures at the thoracolumbar spine in patients between 60 and 70 years of age.

作者信息

Spiegl Ulrich J, Devitt Brian M, Kasivskiy Ihor, Jarvers Jan-Sven, Josten Christoph, Heyde Christoph-Eckhard, Fakler Hannes M

机构信息

Department of Orthopaedics, Trauma Surgery and Plastic Surgery, University of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.

Department of Hip Arthroscopy, Hip Arthroscopy Australia, 21-23 Erin Street, Melbourne, VIC, 3121, Australia.

出版信息

Arch Orthop Trauma Surg. 2018 Oct;138(10):1407-1414. doi: 10.1007/s00402-018-2993-y. Epub 2018 Jul 14.

Abstract

INTRODUCTION

Surgical treatment of unstable burst fractures of the thoracolumbar spine in the elderly population is highly variable with combined posterior and anterior stabilization (CPAS) and posterior augmented stabilization with cementation of the vertebral body (hybrid) being two commonly used techniques. The aim of this study was to compare the clinical and radiographic outcomes of CPAS versus hybrid stabilization for the treatment of unstable burst fractures of the thoracolumbar spine in patients aged between 60 and 70 years.

MATERIALS AND METHODS

A retrospective analysis was performed of all thoracolumbar burst fractures treated surgically in a single level I trauma center between June 2013 and February 2015. Two commonly used strategies of surgical stabilization were compared; the first consisted of initial posterior reduction and bisegmental stabilization, followed by additional anterior spondylodesis (CPAS); the second method comprised a hybrid technique with a posterior cement augmented bisegmental minimally invasive stabilization and kyphoplasty of the fractured vertebral body. Patients were evaluated clinically after a minimum follow-up of 18 months. The primary endpoint was the Oswestry Disability Index (ODI) at the latest follow-up. Secondary parameters of interest were length of in-hospital stay (LIHS), duration of surgery (DS), surgical revisions (SR), pain level (P-VAS), satisfaction level and the SF-36 score (PSC, MSC), the bisegmental postoperative Cobb angle, the reduction loss (RL), and all alignment parameters (pelvic tilt, pelvic incidence, sacral slope, lumbar lordosis, C7 plumb line).

RESULTS

A total of 29 patients were included (17 females, 12 males, mean age 65.6 years ± 3.4 years). The following vertebral bodies were fractured: thoracic level (T) 12: n = 6; lumbar (L) 1: n = 14; L 2: n = 6; L 3: n = 3. CPAS was performed in 10 patients (34%), whereas the hybrid was carried out in 19 patients (66%). There were no statistical significant differences between both study groups regarding age, gender, trauma energy, fracture level, and fracture morphology. The latest follow-up was performed after a mean of 27 months (range 18-53 months). The LIHS between the treatment methods was statistically significant (p < 0.01); CPAS-mean 24 days versus hybrid-mean 12 days. DS was also significantly longer in patients treated with CPAS, 254 versus 95 min for the hybrid group (p < 0.01). No SR were necessary in either group. No significant differences were found regarding the clinical and radiological outcomes between the groups. The mean ODI score was 13.6 in the CPAS patients compared to 10.8 in the hybrid patients without significant differences between the groups. The majority of patients had no (80%) or minor (13%) limitations according to the ODI score. The P-VAS was 2.8 in CPAS and 2.9 in the hybrid group. RL was 7.1° in CPAS and 4.2° in the hybrid group.

CONCLUSIONS

CPAS and hybrid stabilization provide safe and promising short- and middle-term results in patients between 60 and 70 years of age. The majority of patients demonstrated no disability or minimal limitations with either technique. CPAS resulted in prolonged inpatient hospital stays, longer duration of surgery compared to hybrid stabilization without significant differences in clinical and radiological outcome.

摘要

引言

老年人群胸腰椎不稳定爆裂骨折的手术治疗方式差异很大,后路与前路联合固定(CPAS)和椎体骨水泥强化后路固定(混合手术)是两种常用技术。本研究旨在比较CPAS与混合固定治疗60至70岁患者胸腰椎不稳定爆裂骨折的临床和影像学结果。

材料与方法

对2013年6月至2015年2月间在某一级创伤中心接受手术治疗的所有胸腰椎爆裂骨折进行回顾性分析。比较两种常用的手术固定策略:第一种包括先行后路复位和双节段固定,随后进行前路椎体间融合术(CPAS);第二种方法是采用混合技术,即后路骨水泥强化双节段微创固定并对骨折椎体进行后凸成形术。患者至少随访18个月后进行临床评估。主要终点是最后一次随访时的Oswestry功能障碍指数(ODI)。其他感兴趣的次要参数包括住院时间(LIHS)、手术时长(DS)、手术翻修情况(SR)、疼痛程度(P-VAS)、满意度以及SF-36评分(PSC、MSC)、术后双节段Cobb角、复位丢失(RL)以及所有对线参数(骨盆倾斜度、骨盆入射角、骶骨坡度、腰椎前凸、C7铅垂线)。

结果

共纳入29例患者(17例女性,12例男性,平均年龄65.6岁±3.4岁)。骨折椎体节段如下:胸12(T12):n = 6;腰1(L1):n =14;腰2(L2):n = 6;腰3(L3):n = 3。10例患者(34%)接受CPAS治疗,19例患者(66%)接受混合手术治疗。两组在年龄、性别、创伤能量、骨折节段及骨折形态方面无统计学显著差异。最后一次随访平均在术后27个月(范围18 - 53个月)进行。两种治疗方法的LIHS有统计学显著差异(p < 0.01);CPAS组平均24天,混合手术组平均12天。接受CPAS治疗患者的DS也显著更长,CPAS组为254分钟,混合手术组为95分钟(p < 0.01)。两组均无需手术翻修。两组在临床和影像学结果方面未发现显著差异。CPAS组患者的平均ODI评分为13.6,混合手术组为10.8,两组间无显著差异。根据ODI评分,大多数患者无(80%)或仅有轻微(13%)功能受限。CPAS组的P-VAS为2.8,混合手术组为2.9。CPAS组的RL为7.1°,混合手术组为4.2°。

结论

CPAS和混合固定为60至70岁患者提供了安全且有前景的短期和中期结果。大多数患者采用两种技术中的任何一种均未出现功能障碍或仅有极小的功能受限。与混合固定相比,CPAS导致住院时间延长、手术时长增加,但临床和影像学结果无显著差异。

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