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缺血性结肠炎导致早期和晚期死亡率增加。

Ischemic colitis caused increased early and delayed mortality.

机构信息

Department of General Surgery, Rambam Health Care Campus, Hayim Gilshtein, 8 Haalia Street, Haifa, Israel.

出版信息

World J Emerg Surg. 2018 Jul 11;13:31. doi: 10.1186/s13017-018-0193-2. eCollection 2018.

DOI:10.1186/s13017-018-0193-2
PMID:30008799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6042445/
Abstract

BACKGROUND

Ischemic colitis remains a challenge for the surgeon, both in its diagnosis and treatment. Data from a single tertiary center, of patients diagnosed with ischemic colitis, was collected. An attempt was made to delineate the patients requiring surgical intervention.

METHODS

A retrospective study was undertaken in patients diagnosed with ischemic colitis admitted to Rambam Health Care Campus between 2011 and 2016. The primary outcome was defined as mortality. Secondary outcomes were defined as complications during conservative treatment and postoperative course.

RESULTS

Sixty-three patients were diagnosed with ischemic colitis during the study period. The mean age at presentation was 72.5 years, with a female predominance (62%). The overall mortality rate was 29% (18/63). Six patients (50%) of those operated died. An older age, comorbidities and higher lactate levels present risk factors for a worse outcome.

CONCLUSIONS

Ischemic colitis continues to present a challenge in its management. A better understanding of the disease process is required. And one needs to adhere to sound surgical principles for a timely diagnosis and treatment, especially in older patients with worrisome clinical, laboratory, and imaging features.

摘要

背景

缺血性结肠炎仍然是外科医生面临的挑战,无论是在诊断还是治疗方面。收集了在单一三级医疗中心诊断为缺血性结肠炎的患者的数据。试图明确需要手术干预的患者。

方法

对 2011 年至 2016 年期间入住 Rambam 医疗保健园区的缺血性结肠炎患者进行回顾性研究。主要结局定义为死亡率。次要结局定义为保守治疗和术后过程中的并发症。

结果

在研究期间,63 名患者被诊断为缺血性结肠炎。发病时的平均年龄为 72.5 岁,女性居多(62%)。总体死亡率为 29%(18/63)。接受手术的 6 名患者(50%)死亡。年龄较大、合并症和较高的乳酸水平是预后不良的危险因素。

结论

缺血性结肠炎在其治疗中仍然存在挑战。需要更好地了解疾病过程。需要遵循合理的外科原则,以便及时诊断和治疗,特别是在有令人担忧的临床、实验室和影像学特征的老年患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b72/6042445/30f6c1d8c8f5/13017_2018_193_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b72/6042445/30f6c1d8c8f5/13017_2018_193_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b72/6042445/30f6c1d8c8f5/13017_2018_193_Fig1_HTML.jpg

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