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一例由霍奇金淋巴瘤引起的后天性食管-肺瘘的罕见病例。

An Unusual Case of an Acquired Esophageal-pulmonary Fistula Caused by Hodgkin Lymphoma.

作者信息

Gonzalez Juan J, Talasila Lakshmi, Ochoa Lisa, Youssef John, Adekolujo Orimisan S

机构信息

Internal Medicine Department, Mclaren Flint, Michigan State University, Flint, USA.

出版信息

Cureus. 2018 May 7;10(5):e2589. doi: 10.7759/cureus.2589.

DOI:10.7759/cureus.2589
PMID:30009103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6037330/
Abstract

Bronchoesophageal and tracheoesophageal fistulas are an uncommon but well-documented complication of Hodgkin lymphoma (HL). To our knowledge, a fistula directly connecting the esophagus with the lung (esophageal-pulmonary fistula) and resulting from HL has not been reported in the literature. We present a case of HL complicated with an esophageal-pulmonary fistula. The early recognition and treatment of an esophageal-pulmonary fistula in patients with HL are imperative since, with appropriate treatment, HL complicated with an aero-esophageal fistula has the same prognosis as those without one, unlike the dismal prognosis in esophageal and lung cancer. Endoscopic esophageal stenting followed by chemotherapy is the preferred treatment approach. This leads to the healing of the fistula and the prolongation of patient survival.

摘要

支气管食管瘘和气管食管瘘是霍奇金淋巴瘤(HL)一种罕见但有充分文献记载的并发症。据我们所知,文献中尚未报道过HL导致的食管与肺直接相通的瘘(食管-肺瘘)。我们报告一例HL并发食管-肺瘘的病例。HL患者食管-肺瘘的早期识别和治疗至关重要,因为通过适当治疗,HL并发气食管瘘的预后与未并发者相同,这与食管癌和肺癌的预后不佳不同。内镜下食管支架置入术联合化疗是首选的治疗方法。这可使瘘愈合并延长患者生存期。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5517/6037330/edcee150136b/cureus-0010-00000002589-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5517/6037330/ad9e95c380e5/cureus-0010-00000002589-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5517/6037330/99803c7439aa/cureus-0010-00000002589-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5517/6037330/edcee150136b/cureus-0010-00000002589-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5517/6037330/ad9e95c380e5/cureus-0010-00000002589-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5517/6037330/99803c7439aa/cureus-0010-00000002589-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5517/6037330/edcee150136b/cureus-0010-00000002589-i03.jpg

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本文引用的文献

1
Healing of a large bronchoesophageal fistula secondary to hodgkin lymphoma managed with a removable esophageal stent.可移除食管支架治疗霍奇金淋巴瘤所致大支气管食管瘘的愈合。
Ann Thorac Surg. 2013 Dec;96(6):2216-9. doi: 10.1016/j.athoracsur.2013.02.066.
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Late relapse of Hodgkin's lymphoma presenting as fatal hematemesis caused by an esophago-tracheo-arterial fistula.霍奇金淋巴瘤晚期复发表现为食管气管动脉瘘导致的致命性呕血。
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Lymphoma and tracheoesophageal fistula: Indication for a removable esophageal stent.
淋巴瘤与气管食管瘘:可取出食管支架的适应证
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Malignant tracheoesophageal fistula.恶性气管食管瘘
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Tracheoesophageal fistula due to cancer.癌症导致的气管食管瘘
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Tracheoesophageal fistula in the patient with lymphoma: case report and review of the literature.淋巴瘤患者的气管食管瘘:病例报告及文献复习
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Malignant esophagorespiratory fistula: management options and survival.恶性食管气管瘘:治疗选择与生存情况
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The occurrence and management of esophageal fistulas resulting from Hodgkin's disease.霍奇金病所致食管瘘的发生与处理
Cancer. 1992 Feb 15;69(4):1031-3. doi: 10.1002/1097-0142(19920215)69:4<1031::aid-cncr2820690433>3.0.co;2-q.