Ramirez-Zamora Adolfo, Eisinger Robert S, Haider Sameah A, Youn Youngwon, Shin Damian, Molho Eric S, Pilitsis Julie G
Department of Neurology Center for Movement Disorders and Neurorestoration Fixel Center for neurological disorders at the University of Florida Gainesville Florida.
Department of Neurosurgery Henry Ford Hospital Detroit Michigan.
Ann Clin Transl Neurol. 2018 May 21;5(7):865-869. doi: 10.1002/acn3.573. eCollection 2018 Jul.
Deep brain stimulation is a recognized and effective treatment for several movement disorders. Nevertheless, the efficacy of this intervention on abnormal movements secondary to structural brain pathologies is less consistent. In this report, we describe a case of hemiballism-hemichorea due to a peripartum ischemic stroke-treated with deep brain stimulation of the globus pallidus internus. Patient observed marked improvement in her symptoms at long-term follow-up. Neurophysiologic data revealed lower globus pallidus internus firing rates compared to other hyperkinetic disorders. Pallidal deep brain stimulation is a plausible option for medically refractory hemiballism-hemichorea and cumulative data from multiple centers may be used to fully evaluate its efficacy.
深部脑刺激是治疗多种运动障碍的一种公认且有效的方法。然而，这种干预措施对继发于脑部结构病变的异常运动的疗效并不一致。在本报告中，我们描述了一例因围产期缺血性卒中导致的偏侧投掷症-偏侧舞蹈症患者，该患者接受了内侧苍白球深部脑刺激治疗。在长期随访中，患者症状有明显改善。神经生理学数据显示，与其他运动亢进性疾病相比，内侧苍白球的放电率较低。苍白球深部脑刺激是药物难治性偏侧投掷症-偏侧舞蹈症的一种可行选择，多个中心的累积数据可用于全面评估其疗效。
