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儿童胆管损伤:早期内镜逆行胰胆管造影术有作用吗?

Bile Duct Injury in Children: Is There a Role for Early Endoscopic Retrograde Cholangiopancreatography?

作者信息

Aljahdali Akram H, Murphy James J

机构信息

Department of Surgery Johns Hopkins Aramco Healthcare Center, Dhahran, Saudi Arabia.

Division of Pediatric Surgery, Department of Surgery, University of Vermont Medical Center, Burlington, Vermont.

出版信息

Surg J (N Y). 2018 Jul 12;4(3):e119-e122. doi: 10.1055/s-0038-1665550. eCollection 2018 Jul.

DOI:10.1055/s-0038-1665550
PMID:30009264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6043242/
Abstract

Liver injury is common among pediatric abdominal trauma. Nonoperative management is the standard of care in isolated stable liver injuries. Bile leak is not an uncommon complication in moderate- and high-grade injuries.  Three pediatric patients (age: 10-15 years) suffered grade IV liver injuries secondary to blunt abdominal trauma. All developed significant bile leak treated nonoperatively with endoscopic retrograde cholangiopancreatography (ERCP), and patients 1 and 2 were treated with bile duct stent alone. Patient 3 required laparotomy for bile peritonitis and abdominal compartment syndrome followed by interval ERCP and bile duct stent.  Traumatic bile leaks if not recognized and managed early can result in significant morbidity. This paper describes the presentation and treatment of three pediatric patients with blunt liver trauma complicated by significant bile leaks that were managed successfully with ERCP and bile duct stent. This paper demonstrates the importance of early detection of bile leak to prevent bile peritonitis. Abdominal imaging 4 to 5 days postinjury can help in detecting bile accumulation. We believe that ERCP and bile duct stent are becoming the standard of care in diagnosing and treating traumatic bile leak. This paper confirms the safety and feasibility of this technique in the pediatric population.

摘要

肝损伤在小儿腹部创伤中很常见。非手术治疗是单纯稳定型肝损伤的标准治疗方法。胆汁漏在中、重度损伤中是一种常见的并发症。

三名儿科患者(年龄:10 - 15岁)因钝性腹部创伤导致IV级肝损伤。所有患者均出现明显胆汁漏,采用内镜逆行胰胆管造影术(ERCP)进行非手术治疗,患者1和患者2仅接受胆管支架置入治疗。患者3因胆汁性腹膜炎和腹腔间隔室综合征接受剖腹手术,随后进行间隔性ERCP和胆管支架置入。

外伤性胆汁漏如果未被早期识别和处理,可能导致严重的发病率。本文描述了三名小儿钝性肝创伤合并明显胆汁漏患者的临床表现及治疗情况,这些患者通过ERCP和胆管支架置入成功治愈。本文证明了早期发现胆汁漏以预防胆汁性腹膜炎的重要性。受伤后4至5天的腹部影像学检查有助于发现胆汁积聚。我们认为ERCP和胆管支架置入正成为诊断和治疗外伤性胆汁漏的标准治疗方法。本文证实了该技术在儿科人群中的安全性和可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f89/6043242/905fbf4d5167/10-1055-s-0038-1665550-i1700034cr-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f89/6043242/11fffe791bcd/10-1055-s-0038-1665550-i1700034cr-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f89/6043242/b6ca0dc1f7a4/10-1055-s-0038-1665550-i1700034cr-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f89/6043242/905fbf4d5167/10-1055-s-0038-1665550-i1700034cr-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f89/6043242/11fffe791bcd/10-1055-s-0038-1665550-i1700034cr-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f89/6043242/b6ca0dc1f7a4/10-1055-s-0038-1665550-i1700034cr-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f89/6043242/905fbf4d5167/10-1055-s-0038-1665550-i1700034cr-4.jpg

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本文引用的文献

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J Pediatr Surg. 2015 Feb;50(2):335-8. doi: 10.1016/j.jpedsurg.2014.08.017. Epub 2014 Dec 23.
2
Traumatic bile leaks from blunt liver injury in children: a multidisciplinary and minimally invasive approach to management.儿童钝性肝损伤所致创伤性胆漏:一种多学科微创治疗方法
J Pediatr Surg. 2014 Mar;49(3):424-7. doi: 10.1016/j.jpedsurg.2013.07.015.
3
Endoscopic management of traumatic hepatobiliary injuries.
创伤性肝胆损伤的内镜治疗
J Gastroenterol Hepatol. 2007 Aug;22(8):1205-9. doi: 10.1111/j.1440-1746.2006.04780.x.
4
Endoscopic management of traumatic bile leaks.创伤性胆漏的内镜治疗
Gastrointest Endosc. 2007 Jun;65(7):1081-5. doi: 10.1016/j.gie.2006.11.038.
5
Minimally invasive management of bile leaks after blunt liver trauma in children.儿童钝性肝外伤后胆漏的微创治疗
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6
Complications of nonoperative management of pediatric blunt hepatic injury: Diagnosis, management, and outcomes.小儿钝性肝损伤非手术治疗的并发症:诊断、处理及结果
J Trauma. 2006 Aug;61(2):334-9. doi: 10.1097/01.ta.0000197605.27190.2c.
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Traumatic pediatric bile duct injury: nonoperative intervention as an alternative to surgical intervention.创伤性小儿胆管损伤:非手术干预作为手术干预的替代方法。
J Pediatr Surg. 2006 May;41(5):943-5. doi: 10.1016/j.jpedsurg.2006.01.057.
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Diagnostic and therapeutic endoscopic retrograde cholangiopancreatography in children: a large series report.儿童诊断性和治疗性内镜逆行胰胆管造影术:一项大型系列报告
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