氧化氘增强遗传毒性剂诱导的大肠杆菌SOS反应。
Deuterium Oxide Enhances Escherichia coli SOS Response Induced by Genotoxicants.
作者信息
Abilev S K, Smirnova S V, Igonina E V, Parmon V N, Yankovsky N K
机构信息
Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119333, Russia.
Faculty of Biology, Moscow State University, Moscow, 119991, Russia.
出版信息
Dokl Biol Sci. 2018 May;480(1):85-89. doi: 10.1134/S0012496618030031. Epub 2018 Jul 16.
PMID:30009346
Abstract
It has been demonstrated that deuterium oxide enhances the SOS response of Escherichia coli cells induced by chemical genotoxicants and mutagens. This demonstrates that the heavy nonradioactive hydrogen isotope deuterium can be considered to be a comutagen.
摘要
已经证明，氧化氘可增强化学遗传毒性剂和诱变剂诱导的大肠杆菌细胞的SOS反应。这表明重的非放射性氢同位素氘可被视为一种共诱变剂。
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