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鞘内注射巴氯芬疗法——实用方法:临床益处与并发症管理

Intrathecal Baclofen Therapy-Practical Approach: Clinical Benefits and Complication Management.

作者信息

Winter Gidon, Beni-Adani Liana, Ben-Pazi Hilla

机构信息

1 Pediatric Movement Disorders, Neuropediatric Unit, Shaare Zedek Medical Center, Jerusalem.

2 Pediatric Neurosurgery, Shaare Zedek Medical Center, Jerusalem.

出版信息

J Child Neurol. 2018 Oct;33(11):734-741. doi: 10.1177/0883073818785074. Epub 2018 Jul 16.

DOI:10.1177/0883073818785074
PMID:30009656
Abstract

Intrathecal baclofen is an expanding accepted treatment for children with cerebral palsy and other causes of spasticity and dystonia. The aims of this review are therefore to (1) delineate the clinical benefits of intrathecal baclofen therapy in pediatric spasticity and dystonia and (2) increase awareness of the potential complications and emergency management measures of intrathecal baclofen therapy. A current literature review demonstrates the benefits and complications of this minimally invasive device. Practical guides for recognizing acute conditions and management recommendations are included. Intrathecal baclofen is increasingly being used to help individuals attain realistic functional goals. Therefore, families and health care professionals should be aware of potential complications, symptoms, and emergency management.

摘要

鞘内注射巴氯芬是一种越来越被广泛接受的治疗小儿脑瘫及其他痉挛和肌张力障碍病因的方法。因此,本综述的目的是:(1)阐述鞘内注射巴氯芬疗法对小儿痉挛和肌张力障碍的临床益处;(2)提高对鞘内注射巴氯芬疗法潜在并发症及应急处理措施的认识。当前的文献综述展示了这种微创设备的益处和并发症。文中还包括了识别急性病症的实用指南及处理建议。鞘内注射巴氯芬越来越多地被用于帮助患者实现切实可行的功能目标。因此,家庭和医疗保健专业人员应了解潜在的并发症、症状及应急处理方法。

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Intrathecal Baclofen Therapy-Practical Approach: Clinical Benefits and Complication Management.鞘内注射巴氯芬疗法——实用方法:临床益处与并发症管理
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Use of intrathecal baclofen therapy in ambulant children and adolescents with spasticity and dystonia of cerebral origin: a systematic review.鞘内注射巴氯芬治疗脑源性痉挛和肌张力障碍的可移动儿童和青少年:系统综述。
Dev Med Child Neurol. 2011 Oct;53(10):885-95. doi: 10.1111/j.1469-8749.2011.03992.x. Epub 2011 Jun 3.

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