Griesser G H, Hansmann M L
J Cancer Res Clin Oncol. 1985;110(3):238-43. doi: 10.1007/BF00399281.
Two cases of soft tissue sarcoma following treatment of nodular sclerosing Hodgkin's disease are described. One patient developed a malignant schwannoma after radiotherapy, the other was diagnosed as having a malignant fibrous histiocytoma after treatment with radiation and chemotherapy. Both secondary malignancies arose within the irradiated field after a latent period ranging from 9.5 years in the first to 21 years in the second case. A review of the pertinent literature is given and previous reports of malignant tumors and leukemias following therapy for Hodgkin's disease are summarized.
本文描述了两例在结节硬化型霍奇金病治疗后发生软组织肉瘤的病例。一名患者在放疗后发生恶性神经鞘瘤，另一名患者在放疗和化疗后被诊断为恶性纤维组织细胞瘤。两例继发性恶性肿瘤均在放疗区域内发生，潜伏期从第一例的9.5年到第二例的21年不等。本文对相关文献进行了综述，并总结了既往关于霍奇金病治疗后发生恶性肿瘤和白血病的报道。
