Rubins J, Sischy B, Lee J C
Am J Clin Pathol. 1980 Nov;74(5):696-700. doi: 10.1093/ajcp/74.5.696.
A patient in whom an undifferentiated non-Hodgkin's lymphoma developed after treatment for Hodgkin's disease is described. The second tumor occurred eight years after the initial diagnosis, two years after the completion of combined radiation therapy and combination chemotherapy. The pertinent literature is reviewed, with an emphasis on the potential risk of multimodal antineoplastic treatment's causing secondary neoplasms.
本文描述了一名在接受霍奇金病治疗后发生未分化型非霍奇金淋巴瘤的患者。第二肿瘤在初次诊断后八年出现，在联合放疗和联合化疗结束后两年出现。本文对相关文献进行了综述，重点关注多模式抗肿瘤治疗导致继发性肿瘤的潜在风险。
