Non-Hodgkin's lymphoma following treatment for Hodgkin's disease. Case report and review of the literature.

A patient in whom an undifferentiated non-Hodgkin's lymphoma developed after treatment for Hodgkin's disease is described. The second tumor occurred eight years after the initial diagnosis, two years after the completion of combined radiation therapy and combination chemotherapy. The pertinent literature is reviewed, with an emphasis on the potential risk of multimodal antineoplastic treatment's causing secondary neoplasms.