Winn Caroline Bodi, Artim Stephen C, Jamiel Morgan S, Burns Monika A, Haupt Jennifer L, Fox James G, Muthupalani Sureshkumar
Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Comp Med. 2018 Aug 1;68(4):314-318. doi: 10.30802/AALAS-CM-17-000128. Epub 2018 Jul 16.
A 6-y-old, intact, pair-housed male common marmoset (Callithrix jacchus) presented with acute onset dyspnea and tachypnea immediately after sedation with alfaxalone; a history of gradual weight loss initiated the examination under sedation. Thoracic radiographs revealed significant right-lung consolidation, with a vesicular gas pattern in the right caudodorsal lung field, pleural effusion, and dorsal displacement of the heart. The marmoset was euthanized due to his unstable condition and poor prognosis. At necropsy, the cranial and middle lobes of the right lung were homogenously dark red-brown, enlarged, edematous, and twisted around the longitudinal axis at the hilus. The left lung lobes were pale pink and slightly edematous. In light of the clinical and gross necropsy findings, acute torsion of the right cranial and middle lung lobes was diagnosed. Predisposing conditions for lung lobe torsion include trauma, neoplasia, pulmonary disease, previous thoracic surgery, and diaphragmatic hernia, but none of these applied to this case. Initial therapy for lung lobe torsion is to stabilize the patient and treat for underlying conditions, with prompt surgical resection as the treatment of choice. To our knowledge, this report is the first description of lung lobe torsion in an experimentally unmanipulated New World NHP.
一只6岁、未绝育、成对饲养的雄性普通狨猴(Callithrix jacchus)在使用阿法沙龙镇静后立即出现急性呼吸困难和呼吸急促;逐渐体重减轻的病史促使在镇静状态下进行检查。胸部X光片显示右肺显著实变,右肺尾背侧肺野有小泡状气体分布,胸腔积液,心脏背侧移位。由于病情不稳定且预后不良,该狨猴被实施安乐死。尸检时,右肺的颅叶和中叶均匀地呈暗红色至棕色,肿大、水肿,并在肺门处沿纵轴扭曲。左肺叶呈淡粉色,轻度水肿。根据临床和大体尸检结果,诊断为右颅叶和中叶急性扭转。肺叶扭转的诱发因素包括创伤、肿瘤、肺部疾病、既往胸外科手术和膈疝,但这些情况均不适用于本病例。肺叶扭转的初始治疗是稳定患者病情并治疗潜在疾病,迅速进行手术切除是首选治疗方法。据我们所知,本报告是对一只未经实验操作的新大陆非人灵长类动物肺叶扭转的首次描述。