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未诊断为慢性高血压的女性中高尿酸血症与产后即刻高血压的关联。

The association of hyperuricemia and immediate postpartum hypertension in women without a diagnosis of chronic hypertension.

作者信息

Marrs Caroline C, Rahman Mahbubur, Dixon Luke, Olson Gayle

机构信息

a Division of Maternal Fetal Medicine , The University of Texas Medical Branch , Galveston , TX , USA.

出版信息

Hypertens Pregnancy. 2018 Aug;37(3):126-130. doi: 10.1080/10641955.2018.1493494. Epub 2018 Jul 17.

DOI:10.1080/10641955.2018.1493494
PMID:30014728
Abstract

Our objective was to determine if elevated uric acid (UA) is associated with postpartum hypertension (PP HTN) in women without chronic hypertension. This is a secondary analysis of a randomized trial. We compared those with elevated UA to those with normal UA. Logistic regression was conducted to determine the association of elevated UA with PP HTN. Five hundred and fifty-six women met criteria. An UA level ≥ 5.2 mg/dL was associated with immediate PP HTN (adjusted odds ratio 2.44, 95% CI 1.63-3.64). The association was stronger among overweight and obese women. We conclude that hyperuricemia is associated with PP HTN, especially among obese women.

摘要

我们的目的是确定尿酸(UA)升高是否与无慢性高血压的女性产后高血压(PP HTN)相关。这是一项随机试验的二次分析。我们将尿酸升高的女性与尿酸正常的女性进行了比较。采用逻辑回归分析来确定尿酸升高与PP HTN之间的关联。556名女性符合标准。尿酸水平≥5.2mg/dL与即刻PP HTN相关(校正比值比2.44,95%CI 1.63-3.64)。这种关联在超重和肥胖女性中更强。我们得出结论,高尿酸血症与PP HTN相关,尤其是在肥胖女性中。

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