Rastawicki Waldemar, Formińska Kamila, Zasada Aleksandra A
Department of Bacteriology, National Institute of Public Health - National Institute of Hygiene,Warsaw,Poland.
Department of Sera and Vaccines Evaluation, National Institute of Public Health - National Institute of Hygiene,Warsaw,Poland.
Pol J Microbiol. 2018 Jun 30;67(2):241-244. doi: 10.21307/pjm-2018-030.
Francisella tularensis are highly infectious bacteria causing a zoonotic disease called tularemia. Identification of this bacterium is based on antigen detection or PCR. The paper presents a latex agglutination test (LAT) for rapid identification of clinically relevant F. tularensis subspecies. The test can be performed within three minutes with live or inactivated bacteria. The possibility to test the inactivated samples reduces the risk of laboratory acquired infection and allows performing the test under BSL-2 conditions.
土拉弗朗西斯菌是一种极具传染性的细菌,可引发一种名为兔热病的人畜共患病。对这种细菌的鉴定基于抗原检测或聚合酶链反应(PCR)。本文介绍了一种乳胶凝集试验(LAT),用于快速鉴定临床相关的土拉弗朗西斯菌亚种。该试验可在三分钟内使用活菌或灭活菌进行。检测灭活样本的可能性降低了实验室获得性感染的风险,并允许在生物安全二级(BSL-2)条件下进行试验。