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[氨苯砜所致高铁血红蛋白血症:1例儿科病例报告]

[Methemoglobinemia due to Dapsone: a pediatric case report].

作者信息

Paccor Ayelén, Matsuda Mariana, Capurso Cintia, Rizzo Elizabeth, Larroca M Celeste

机构信息

Hospital Zonal de Agudos "Magdalena V. de Martínez", Pacheco, Buenos Aires.

出版信息

Arch Argent Pediatr. 2018 Aug 1;116(4):e612-e615. doi: 10.5546/aap.2018.e612.

Abstract

Methemoglobinemia is a condition characterized by a high blood concentration of methemoglobin. Methemoglobinemia is a disorder that occurs when hemoglobin in the blood is oxidized to form methemoglobin, rendering it unable to transport oxygen. Although it can be congenital in cyanotic newborn, it is more often an adverse medication effect. The aim is to report a pediatric methemoglobinemia case, assisted in Magdalena V. de Martínez Hospital, with cyanosis in face and limb, in poor condition, that consumed dapsone accidentally. Her methemoglobin concentration was 35%. Intravenous methylene blue was administered with favorable outcome.

摘要

高铁血红蛋白血症是一种以血液中高铁血红蛋白浓度升高为特征的病症。高铁血红蛋白血症是一种当血液中的血红蛋白被氧化形成高铁血红蛋白,使其无法运输氧气时发生的疾病。虽然它在患有青紫症的新生儿中可能是先天性的,但更常见的是药物不良反应。目的是报告一例在马格达莱纳·V·德·马丁内斯医院救治的小儿高铁血红蛋白血症病例,该患儿面部和四肢青紫,情况不佳,意外服用了氨苯砜。其高铁血红蛋白浓度为35%。静脉注射亚甲蓝后取得了良好效果。

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