亚利桑那州凤凰城班纳好撒玛利亚医疗中心医学毒理学奖学金病例档案：接触氨苯砜后出现高铁血红蛋白血症。
Case files of the medical toxicology fellowship at Banner Good Samaritan Medical Center in Phoenix, AZ: methemoglobinemia following dapsone exposure.
机构信息
Department of Medical Toxicology, Banner Good Samaritan Medical Center, Phoenix, AZ, USA.
出版信息
J Med Toxicol. 2011 Jun;7(2):139-46. doi: 10.1007/s13181-011-0151-9.
Abstract
Acquired methemoglobinemia is a common, potentially fatal syndrome that can occur as a result of exposure to numerous xenobiotics. A case report of a 14-month-old female who developed methemoglobinemia following a dapsone ingestion. The child was treated with numerous boluses of methylene blue and ultimately required a continuous infusion of methylene blue. The common causes of methemoglobinemia, as well as the underlying pathophysiology, diagnosis, and treatment strategies are discussed.
摘要
获得性高铁血红蛋白血症是一种常见的、潜在致命的综合征，可能由于暴露于许多外源性物质而发生。本文报告了一例 14 个月大的女性在服用氨苯砜后发生高铁血红蛋白血症的病例。该患儿接受了多次亚甲蓝推注治疗，最终需要持续输注亚甲蓝。讨论了高铁血红蛋白血症的常见原因以及潜在的病理生理学、诊断和治疗策略。
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