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克赖斯特彻奇市人类嗜T淋巴细胞病毒III型筛查试验评估

Assessment of HTLV III screening tests in Christchurch.

作者信息

Field D, Whyte G, Robertson S

出版信息

N Z Med J. 1985 Nov 27;98(791):992-3.

PMID:3001606
Abstract

The Christchurch Hospital blood bank has assessed commercial kits designed to test blood donations for the presence of antibody to the retrovirus responsible for acquired immune deficiency syndrome (AIDS). Twenty of 1002 blood donations have been found to be repeatably, positive by one or more of these commercial kits. None was positive by the Western blot technique. Certain patient groups were found to have an elevated number of false positive reactions. Extreme caution is advised when interpreting screening test kit results from donor populations at low risk of AIDS.

摘要

克赖斯特彻奇医院血库对旨在检测献血者体内是否存在导致获得性免疫缺陷综合征(艾滋病)的逆转录病毒抗体的商用试剂盒进行了评估。在1002份献血样本中,有20份被一种或多种此类商用试剂盒反复检测为阳性。而采用蛋白质印迹法检测时,这些样本均为阴性。研究发现,某些患者群体的假阳性反应数量有所增加。在解读来自艾滋病低风险献血人群的筛查试剂盒结果时,建议格外谨慎。

相似文献

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Screening for AIDS.
Med Lett Drugs Ther. 1985 Mar 29;27(684):29-30.
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Screening blood: public health and medical uncertainty.
Hastings Cent Rep. 1985 Aug;15(4):suppl 8-11.

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