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丝氨酸磷脂与衰老大脑

Serine phospholipids and aging brain.

作者信息

Calderini G, Aporti F, Bonetti A C, Zanotti A, Toffano G

出版信息

Prog Clin Biol Res. 1985;192:383-6.

PMID:3001763
Abstract

For many years phospholipids have been studied mainly for their possible use as membrane models or cell-like carriers. Recently, on the basis of the new knowledge on the phospholipid membrane structure and function, a novel interest has arisen on the pharmacological properties of these compounds particularly at cerebral level. In this context particular attention has been devoted to phosphatidylserine (BC-PS), an anionic phospholipid extracted and purified from bovine brain, which in young animals has been shown to modify a number of brain electrophysiological and biochemical parameters.

摘要

多年来,磷脂主要因其作为膜模型或类细胞载体的潜在用途而受到研究。最近,基于对磷脂膜结构和功能的新知识,人们对这些化合物的药理特性产生了新的兴趣,尤其是在脑水平上。在这种背景下,人们特别关注磷脂酰丝氨酸(BC-PS),一种从牛脑中提取和纯化的阴离子磷脂,在幼小动物中,它已被证明能改变许多脑电生理和生化参数。

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Serine phospholipids and aging brain.丝氨酸磷脂与衰老大脑
Prog Clin Biol Res. 1985;192:383-6.
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Comparison of molecular species of various transphosphatidylated phosphatidylserine (PS) with bovine cortex PS by mass spectrometry.通过质谱法比较各种转磷脂酰化磷脂酰丝氨酸(PS)与牛脑皮质PS的分子种类。
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