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Oncolytic Virotherapy: Single Cycle Cures or Repeat Treatments? (Repeat Dosing Is Crucial!).

作者信息

Melcher Alan

机构信息

Institute of Cancer Research, Department of Radiotherapy and Imaging, London, UK.

出版信息

Mol Ther. 2018 Aug 1;26(8):1875-1876. doi: 10.1016/j.ymthe.2018.07.002. Epub 2018 Jul 14.

Abstract
摘要

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本文引用的文献

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Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy.
Mol Ther. 2018 Apr 4;26(4):1008-1019. doi: 10.1016/j.ymthe.2018.01.019. Epub 2018 Jan 31.
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Antitumor Benefits of Antiviral Immunity: An Underappreciated Aspect of Oncolytic Virotherapies.
Trends Immunol. 2018 Mar;39(3):209-221. doi: 10.1016/j.it.2017.11.006. Epub 2017 Dec 20.
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Immune-mediated antitumor activity of reovirus is required for therapy and is independent of direct viral oncolysis and replication.
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10

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